BACKGROUND AND OBJECTIVES The incidence of postoperative vomiting in patients undergoing laparoscopic cholecystectomy is compared in females versus males. The report also compares the prophylactic action of ondansetron versus metoclopramide. METHODS A total of 85 American Society of Anesthesiologists (ASA) I and II patients were enrolled in the study. Patients were divided into two groups acc...

BACKGROUND Post-operative nausea and vomiting is one of the most frequently occurring side effects affecting one third of the cases. Objective of the study was to compare the efficacy of ondansetron alone and ondansetron plus dexamethasone in preventing postoperative nausea and vomiting after middle ear surgery. METHODS This randomized controlled trial was conducted at the Anaesthesia and ENT...

Background. The prophylactic administration of ondansetron has been reported to provide a protective effect against hypotension in spinal anaesthesia (SA). Material and methods. This prospective double-blind, randomised, placebo-controlled study included 130 healthy pregnant women scheduled for elective caesarean delivery under SA randomly allocated to receive placebo (n = 65) or ondansetron 8 ...

UNLABELLED OBJCTIVE: The objectives were to evaluate the safety and efficacy of ondansetron in the out-of-hospital treatment of undifferentiated nausea or vomiting. METHODS Patients with severe nausea or intractable vomiting who were transported by paramedic-staffed ambulances in eight California counties were treated with intravenous (IV), intramuscular (IM), or oral dissolving tablet (ODT) ...

OBJECTIVE To evaluate whether ondansetron or the combination of doxylamine and pyridoxine was superior for the treatment of nausea and vomiting of pregnancy. METHODS This was a double-blind, randomized, controlled trial in which women with nausea and vomiting of pregnancy were assigned to 4 mg of ondansetron plus a placebo tablet or 25 mg pyridoxine plus 12.5 mg of doxylamine for 5 days. The ...

Background: Propofol, most frequently used intravenous anaesthetic, is used for induction, maintenance of anaesthesia and for sedation in patients scheduled for routine elective surgical procedure. A unique action of propofol is its antiemetic effect, which remain present at concentration less than producing sedation. Pain on injection of propofol still remains a considerable concern for the an...

Nausea and vomiting are common side effects of opioids administered for pain control. This double-blind, randomized, parallel-group study evaluated the anti-emetic efficacy and tolerability of single intravenous (i.v.) doses of ondansetron 8 mg, ondansetron 16 mg and metoclopramide 10 mg in the treatment of opioid-induced emesis. Adult patients undergoing low emetogenic surgical procedures, usi...

Unfortunately, it is not fully known what exactly causes clinical depression for a particular individual. There are many theories about causes such as biological and genetic factors, environmental influences. Complications with depression may include excess weight which can lead to heart disease and diabetes, family conflicts, social isolation. This study aimed at evaluating the antidepressant ...

BACKGROUND Postoperative shivering is one of the common problems following general anesthesia and may lead to multiple complications. The aim of this study was to examine the preventive effects of Ondansetron and Meperidine on postoperative shivering. METHODS This randomized placebo-controlled double blind clinical trial included 90 patients scheduled for elective gynecologic operations, rand...

BACKGROUND Vomiting is a common sympton in children with gastroenteritis, but its treatment remains controversial. AIM To investigate potential beneficial effects of ondansetron, compared with placebo or no intervention, in treating vomiting during acute gastroenteritis in children. METHODS The following electronic databases were searched through August 2006: MEDLINE, EMBASE, CINAHL and The...