نتایج جستجو برای: p glycoprotein
تعداد نتایج: 1335918 فیلتر نتایج به سال:
The P-glycoprotein is an energy-dependent efflux pump capable of decreasing the intracellular concentration of a broad range of chemotherapeutic agents. [99mTc]Sestamibi, a P-glycoprotein transport substrate, is a sensitive probe of P-glycoprotein function both in vitro and in vivo. A human tumor model in nude mice was evaluated to determine whether [99mTc]Sestamibi could detect in vivo differe...
introduction: in order to determine the multidrug resistance (mdr) phenotype due to p-glycoprotein expression in haematological malignancies including acute myeloblastic leukemia (aml), a well-characterized p-gp expressing cell line was required to validate and standardize flow cytometric assays and to calibrate instruments. therefore, this resistant subline of k562 was established for the firs...
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