List accessing problem has been studied as a problem of significant theoretical and practical interest in the context of linear search. Various list accessing algorithms have been proposed in the literature and their performances have been analyzed theoretically and experimentally. Move-To-Front (MTF), Transpose (TRANS) and Frequency Count (FC) are the three primitive and widely used list acces...

Thirteen monoclonal antibodies to ppp(A2'p5')nA oligonucleotides have been produced by fusing Y3 myeloma cells with spleen cells of rat hyperimmunized with A2'p5'A succinyl albumin as immunogen. 125I-labeled A2'p5'A succinyl tyrosine methyl ester was used as a labeled probe. Antibodies were detected by their ability to bind the labeled analog and were selected for their affinity for A2'p5'A. Th...

Haemophilus parasuis is a Gram-negative respiratory pathogen of young pigs that colonizes the upper respiratory tract and produces a number of symptoms collectiviely described as Glässer's disease. Recently, an H. parasuis P5-like outer membrane adhesin protein homologous to H. influenzae P5 was identified. The P5 adhesin was partially purified by anion exchange and size-exclusion chromatograph...

The use of anti-beta 1 integrin monoclonal antibody in lung cancer treatment has proven beneficial. Here, we developed a novel monoclonal antibody (mAb), called P5, by immunizing mice with human peripheral blood mononuclear cells (PBMC). Its anti-tumor effect is now being tested, in a clinical phase III trial, in combinatorial treatments with various chemical drugs. To confirm that P5 indeed bi...

During the course of persistent infections by nonencapsulated Haemophilus influenzae in patients with chronic bronchitis, the major outer membrane protein (MOMP) P5 varies in molecular weight. The nature of this variability was determined by DNA sequence analysis of the P5 gene from five different H. influenzae strains and their seven MOMP P5 variants which were isolated from patients with chro...

Chemical modification of p5’A2’(p5’A2’),p5’A by a periodate oxidation/Schiff base formation/borohydride reduction cycle gave a series of 2-5A analogues in which the ribose of the 2’-terminal nucleotide was transformed to an N-substituted morpholine (azahexapyranose). 2’,5’-Oligoriboadenylate 5’-monophosphates bearing this modification were 5-10 times more potent as antagonists of the action of ...

A total acquisition move in a weighted graph G moves all weight from a vertex u to a neighboring vertex v, provided that before this move the weight on v is at least the weight on u. The total acquisition number, at(G), is the minimum number of vertices with positive weight that remain in G after a sequence of total acquisition moves, starting with a uniform weighting of the vertices of G. For ...

In [7], Coleman and Mazur construct a rigid analytic space E that parameterizes overconvergent and therefore classical modular eigenforms of finite slope. The geometry of E is at present poorly understood, and seems quite complicated, especially over the centre of weight space. Recently, some progress has been made in understanding the geometry of E in certain examples (see for example [3],[4])...

We give a complete structure description of (P 5 ,gem)-free graphs. By the results of a related paper, this implies bounded clique width for this graph class.

b a ckground: malaria still is considered as a public health problem in iran. the aim of the national malaria control department is to reach the elimination by 2024. by decreasing the number of malaria cases in preelimination phase the cost effectiveness of malaria interventions decreases considerably. this study estimated the cost effectiveness of various strategies to combat malaria in preeli...