Rat and human populations inhabit the same space. Rats as a species have been given different kinds of classifications, from lab fancy rats to pests even circus animals. The sociozoo-logic scale ranks humans higher than other animals within structure meaning that allows hu-mans define, reinforce justify their interactions with beings (DeMello, 2012: 51). Hu-mans...

background: fluoride (f−) is a trace element that is incorporated into bone mineral during bone formation. this study assessed the effect of increasing fluoride doses on the bone formation and microarchitecture on the femur of rats by histological, and histometrical methods. materials and methods: a total of 16 rats was divided into one group of control and three groups of animals that received...

introduction: due to side effects of antiinflammatory drugs such as dexamethasone and indomethacin, there is a less tendency to use them. on the other hand, the use of medicinal plants has been common in the treatment of inflammation since ancient times and also, using of the plants is increasing. present research investigated the antiinflammatory effect of the hydroalcoholic extract of capitol...

background: therapeutic effects of lithium in manic-depressive disorders have been clarified. during the present study, the effects of lithium carbonate have been assessed on apomorphine-induced sniffing in rats. materials and methods: male albino rats were housed in a glass cylinder and food and water were freely available till 60 minutes before the experiment. immediately after apomorphine in...

the aim of this study was to investigate the effect of acute swimming stress on plasma corticosterone and leptin levels in female and male rats. thirty- seven adult male (n=20) and female (n=20) sprague dawley rats (200-250 g weight) were used. the leptin and corticosterone levels were measured following swimming stress (10 minutes) or no stress. plasma leptin and corticosterone were measured b...

background and aims: flavonoids as polyphenolic naturally occurring compounds have antioxidant activity. there is increasing evidence suggests that flavonoids may affect the activity of enzymes. paraoxonase 1 is calcium - dependent enzyme that is present in high density lipoproteins. this enzyme has an important role in the prevention of low density lipoprotein oxidation. we investigated the ef...

several reports have shown the various effects of grape (vitis vinifera) seed extract such as antioxidant, hypotensive, hypolipidemic and vasodilatory effects. the aim of present study was to investigate the effect of grape leaf hydroalcoholic extract on isolated rat tracheal contractions induced by kcl and acetylcholine. the trachea was removed from male adult sprague-dawley rat and placed in ...

3,4-methylenedioxymethamphetamine (mdma) or ecstasy, has had a widely spread popularity among young adults in recent years. kidney toxicity is one of the consequences of ecstasy. the studies have shown that ecstasy is metabolized by cytochrome p450 to reactive electrophil metabolites which detoxify by glutathione (gsh) conjugation. to our knowledge in vivo study of the effect of glutathione on ...

In type 2 diabetes mellitus (DM2), the impaired functions of brain insulin system are associated with weakened transport through blood-brain barrier due to resistance. Insulin deficiency in can be corrected by intranasal administration (II), whose effect may enhanced C-peptide (ICP). this work, we study treating hyperinsulinemic and normoinsulinemic DM2 rats ICP (36 µg/rat/day), II (20 µg/rat/d...