Objective To assess the potential association between TNF-inhibitors and MOGAD Background The of tumor necrosis factor-a (TNF)-inhibitors with MS has previously been suggested, whereas little is known about MOG-IgG-associated disease (MOGAD) in context these drugs. We recently encountered two patients who developed while receiving TNF-inhibitors, prompting a search for similar cases literature ...

This study aims to investigate the effect of five-flavor sophora flavescens enteric-coated capsules (FSEC) on TNF-α-induced inflammatory bowel disease and its molecular mechanism. Wistar Rats were divided into 6 groups: Normal control group (group A): normal diet, drinking water; Model B): 100 μg/L TNF-α; FSEC high-dose C): 100μg/L TNF-α + (432 mg/kg); medium-dose D): (216 low-dose E): (108 Pos...

Background: Tumor necrosis factor alpha is a proinflammatory cytokine and  as  polyvalent initial response of inflammatory cells which facilitated through the creation of coronary atherosclerosis . It also seems that the polymorphism and susceptibility to atherosclerosis is related to TNF-α gene promoter. The purpose of this study was to investigate single nucleotide polymorphis...

BACKGROUND AND AIM: Recurrent aphthous stomatitis (RAS) is a lesion of the oral cavity with an unknown etiology. Several studies have been performed on the role of tumor necrosis factor-alpha (TNF-α) in RAS. The main purpose of this paper was to review TNF-α level and its gene polymorphism in patients with RAS, the factors influencing the production of TNF-α, a...

Assessing tumour necrosis factor-? (TNF-?) levels in the human body has become an essential tool to recognize heart failure (HF). In this work, label-free, rapid, easy use ImmunoFET based on ion-sensitive field effect transistor (ISFET) was developed for detection of TNF-? protein. Monoclonal anti-TNF-? antibodies (anti-TNF-? mAb) were immobilized ISFET gate made silicon nitride (Si3N4) after s...