Infiltration of water into tunnel within a harsh geological formation is vital issue in tunnelling. The consequence impacts due to seepage include rock instability, pore-water pressure impositionand diminution operational capacity. spatial variation rainfall climate change intensifies the threat stability. Likewise, understand scenarios on 3 Bazai irrigation project wasnumerically simulated inS...

Climate change - partly driven by the increasing level of anthropogenic greenhouse gases is affecting energy consumption buildings. This study assesses impact climate on performance It focuses associated with heating in a case prefabricated building UK. The space evaluated using degree-days theory, and actual buildings used to verify outcome analytical approach for estimated consumption. verifi...

Ligand binding and conformational changes that accompany signaling from G protein–coupled receptors (GPCRs) have mostly focused on the role of transmembrane helices and intracellular loop regions. However, recent studies, including several GPCRs cocrystallized with bound ligands, suggest that the extracellular surface (ECS) of GPCRs plays an important role in ligand recognition, selectivity, an...