The Prophylactic Effect of Cuminum cyminum Extract on Gastric Residual Volume in Traumatic Patients under Ventilator Hospitalized in Intensive Care Unit

Background: Increased Gastric residual volume (GRV) is one of the common problems in ICU. Objective: The aim of this study was to determine the effect of cumin extract on gastric residual volume in patients with traumatic episodes hospitalized in ICU. Method: This double-blind randomized clinical trial was conducted on 60 patients traumatic hospitalized in ICU. Patients were randomly assigned to one of two groups: cumin (n = 30) and distilled water (n = 30). In the intervention group, 6 grams of cumin extract in 3 divided doses were given 50 drops in 30 cc of urban water at 3 times every 8 hours after. The remaining volume was recorded for up to 4 consecutive days and the data were compared in two groups. (IRCT: 201610297494N24). Results: Before the intervention, there was no significant difference between the mean GRV in the cumin group and placebo group (P = 0.63). Comparing the two groups of placebo and placebo, there was no significant difference in the amount of residual stomach in hospitalized patients with ICU on the first day (P = 0.13), but on the second, third and fourth days, this difference was significant between the two groups (p = 0.001).Comparing the two groups of intervention and placebo, the average volume of residual stomach before and during 4 consecutive days after intervention was significant (P = 0.001). Conclusion: The results of this study showed that cumin extract was effective in decreasing residual stomach volume in hospitalized patients with ICU in comparison with placebo.