Variation in the outcome following intralesional 5-FU in the treatment of various forms of cutaneous warts in Iraqi patients based on clinical presentation

Results: Response of skin warty lesions to treatment with intralesional 5-FU was as following: complete response was seen in 200 (80.0 %), partial response was seen in 37 (14.8 %) of cases and no response was recorded in 13 (5.2 %) of cases. There was no significant association between size of warty lesion and response to intralesional 5-FU (p = 0.154), but there was significant association between type of warty lesion and response to intralesional 5-FU (p = 0.046) in such a way that complete response was most commonly associated with palmoplanter lesions, whereas, no response was mostly associated with periungual lesions. Conclusion: Intralesional 5-FU appears to be highly effective in treatment of cutaneous warts; however, the response is influenced by type of skin lesion, being maximal with palmoplanter wart and least common with periungual lesions.