Seyed Reza Banihahsemi

Department of Medical Immunology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran

[ 1 ] - Development of specific nanobodies (VHH) for CD19 immuno-targeting of human B-lymphocytes

Objective(s): CD19 is a transmembrane glycoprotein of immunoglobulin superfamily. In order to treat lymphoma, monoclonal antibodies (mAb) can target different antigens, including CD19, CD20 and CD22 on the surface of B-cells. Along with biotechnology progress, a new generation of antibodies is introduced, with the purpose of eliminating the defects of the previous generation. Among the most dev...