Farahnaz Ghahremanfard
Dept. of Internal Medicine, Semnan University of Medical Science, Semnan, Iran
[ 1 ] - Role of Cyclooxygenese-2 (COX-2) Expression in Breast Cancer Differentiation and Its Relationship with Hormone Receptors Status
Background and Objectives: Cyclooxygenese-2 (COX-2) expression in breast cancer and its correlation with tumor prognosis is unclear. We investigated the incidence of COX-2 expression in patients and assessed interactions between COX-2 and clinical features of cancer and expression of HER2/neu, estrogen receptor (ER), and progesterone receptor (PR). Methods: COX-2 expression was investigated by...
[ 2 ] - ارتباط اشباع اکسیژن خون شریانی و اضطراب با شدت تهوع و استفراغ در حین شیمی درمانی
Background: Nausea and vomiting is one of the most important complications in chemotherapy. Serotonin and dopamine are important neurotransmitters in nausea and vomiting. It seems that oxygen therapy and increase oxygen saturation can cause decrease these neurotransmitters. The aim of this study was to investigate the relationship between arterial oxygen saturation (SaO2) of patients and chemot...
[ 3 ] - اثر بربرین بر بیان ژن Bcl-2 در بیماران لوسمی لنفوسیتی مزمن در مقایسه با گروه کنترل
Background and purpose: Anti-apoptotic protein Bcl-2 prevents apoptosis through the mitochondrial pathway and high-level expression of Bcl-2 is required for survival of chronic lymphocytic leukemia (CLL). Berberine (BBR) is an alkaloid that induces apoptosis of cancer cells via mitochondrial pathways. The aim of this study was to investigate the effect of Berberine on Bcl-2 gene expression in p...
[ 4 ] - Effect of IL-27 on activity of bone marrow NK cells of patient with B-chronic lymphocytic leukemia in vitro
Introduction: Functional defect in immune cells is the prominent feature in hematological malignancies that lead to the expansion of tumor cells. Using immunostimulatory cytokines is one of the new therapeutic approaches. This study aimed to investigate the effect of IL-27 on the activity of bone marrow-NK cells of chronic lymphocytic leukemia (CLL) patients in vitro. Materials and Methods: 10 ...
[ 5 ] - Effect of acceptance and commitment group therapy on benefit finding and adherence to treatment in breast cancer patients and survivors: A randomized clinical trial study
Introduction: The positive experience of life changes and the following treatment play a key role in adapting and improving breast cancer. It seems that acceptance and commitment therapy (ACT) helps this issue via facilitating acceptance and clarification of values. Therefore, the current study aimed to evaluate the effectiveness of ACT on the benefit and adherence to treatment in breast cancer...
[ 6 ] - The Prediction of Benefit Finding in Cancer Based on Demographic and Clinical Characteristics, Illness Cognition, and Emotional Processing in Patients Referred to Kosar Specialized Clinic in Semnan in 2020: A Descriptive Study
Background and Objectives: In every disease there are always opportunities for improvement of the individual status, part of which is affected by person's psychological status. Therefore, this study aimed to predict benefit finding in cancer based on demographic and clinical characteristics, illness cognition, and emotional processing in cancer patients. Materials and Methods: This descriptive...