Nader Shahrokhi
Associate Professor of Physiology, Physiology Research Center, Institute of Basic and Clinical Physiology Sciences , Kerman University of Medical Sciences, Kerman, Iran
[ 1 ] - Mumijo Protection gainst Acetaminophen-Induced Acute Hepatic Injury: Role of Oxidative Stress
Background: A majority of people widely use acetaminophen as a sedative. Overusing the drug for prolonged periods of time can lead to acute liver damage. Mumijo, as a strong antioxidant and anti-inflammatory drug, could possibly reduce some of the acetaminophen-induced side effects on the liver. Thus, the aim of this study is to evaluate the effect of Mumijo on the liver damage...
[ 2 ] - اثرات هورمون‌های استروئیدی جنسی بر ادم مغزی و فشار داخل جمجمه‌ای در مدل تجربی ترومای مغزی در موش سفید آزمایشگاهی
سابقه و هدف: در مطالعه حاضر نقش هورمون‌های استروئیدی جنسی بر تغییرات ادم مغزی، فشار داخل جمجمه‌ای ICP)) و فشار پرفیوژن مغزی (CPP) پس از ضربه مغزی در موش‌های صحرایی ماده فاقد تخمدان بررسی شده است. مواد و روش‌ها: دراین پژوهش از موش‌های صحرایی ماده نژاد آلبینو N – ماری که به طور تصادفی به 5 گروه تقسیم شدند استفاده گردید. گروه‌های مورد مطالعه عبارتند از: 1-کنترل، 2- شم، 3- حلال، 4- استروژن (mg/...
[ 3 ] - اثر شیلاجیت بر سطح سایتوکاین های پیش التهابی و ضد التهابی در آسیب کبدی در موش صحرایی نر
Background and purpose: Cytokines regulate a broad range of biological and pathological processes. They play an important role in liver damage. Inflammatory and antioxidant factors are important causes of liver damage. Shilajit is known as an anti-inflammatory and antioxidant agent. Therefore, the main aim of this study was to determine the effect of Shilajit on levels of proinflammat...
[ 4 ] - اثر مصرف خوراکی گیاه بولاغ اوتی (Nasturtium officinale)در کنترل قند و چربی در موش‌های صحرایی دیابتی
Background and Objective: For treating diabetic patients, different nutrients are being used in some areas of Kerman province, Nasturtium offsinallis (NF) is one of them. In current research, effects of NF on plasma lipid and glucose levels have been assessed in diabetic rats. Materials and Methods: In this experimental study, 60 male rats were randomly divided into six groups, consisting, one...
[ 6 ] - Effects of Different Concentrations of Opium on the Secretion of Interleukin-6, Interferon-γ and Transforming Growth Factor Beta Cytokines from Jurkat Cells
Background: The risk of infectious, autoimmune and immunodeficiency diseases and cancers rise in opioid addicts due to changes in innate and acquired immune responses. Three types of opioid receptors (К،δ،μ) are expressed on the surface of lymphocytes and mononuclear phagocytes. The present study was designed to examine the effects of different concentrations of opium on the secretion of some c...
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