ناصحی , محمد
[ 1 ] - تاثیر مهارکننده نیتریک اکساید سنتاز در ناحیه CA1 هیپوکامپ پشتی بر یادگیری وابسته به وضعیت کانابینوئیدها در مدل یادگیری اجتنابی مهاری
Background and purpose: This study presents the effects of nitricoxide synthase inhibitor (L-NAME) on WIN55, 212-2 induced state-dependent memory of passive avoidance task, which were examined in mice. Materials and methods: Mice were anesthetized with intra-peritoneal injection of ketamine hydrochloride, plus xylazine and then placed in a stereotaxic apparatus. Also, two stainless-steel...
[ 2 ] - The Role of Hippocampal 5HT3 Receptors in Harmaline-Induced Memory Deficit
Introduction: The plethora of studies indicated that there is a cross talk relationship between harmaline and serotonergic (5-HT) system on cognitive and non-cognitive behaviors. Thus, the purpose of this study is to assess the effects of hippocampal 5-HT4 receptor on memory acquisition deficit induced by harmaline. Methods: Harmaline was injected peritoneally, while 5-HT4 receptor ago...
[ 3 ] - Transient inactivation of the central amygdala modulates metabolic and hormonal responses to acute stress in female rats
Introduction: Current study examined the possible role of the central nucleus of amygdala (CeA) transient inactivation on the metabolic and hormonal disturbances induced by acute electro foot shock stress in female rats. Considering the differences between female and male in responses to stress, this study attempts to reveal possible mechanisms underlying these differences. Methods: Uni- or bil...
[ 4 ] - Role of L-NAME, a nitric oxide synthase inhibitor, in the improvement of morphine-induced amnesia induced by nicotine
Introduction: Drugs of abuse such as nicotine and morphine used systemically by addicts produce their effects via the mesolimbic dopaminergic pathway. Furthermore, evidence indicates that some behavioral effects of nicotine and morphine are mediated by nitric oxide (NO). Based on these observations, the aim of the present study was to investigate the effects of intra-nucleus accumbens (NAc) ...
[ 5 ] - ترکیب مصرف کورکومین و تمرین شنا بیوژنز میتوکندریایی را پس از مصرف افراطی اتانول در بافت هیپوکامپ رت‌های نر افزایش می‌دهد
سابقه و هدف: یکی از شیوه‌های رایج مصرف اتانول، مصرف افراطی آن می‌باشد که با وجود پرهیز، مصرف آن با اختلالات رفتاری طولانی مدتی همراه است. بنابراین، یافتن روش‌هایی که بتواند در زمانی کوتاه این اختلالات را بهبود بخشد، از اهمیت زیادی برخوردار است. این مطالعه با هدف بررسی اثر کورکومین و تمرین شنا پس از مصرف افراطی اتانول بر بیوژنز میتوکندریایی بافت هیپوکامپ رت‌های نر انجام شد. مواد و روش‌ها: در یک ...
[ 6 ] - اثر تنظیمی آگونیست گیرنده 5-HT4 بر حافظه ترس در هیپوکامپ پشتی موش کوچک آزمایشگاهی
مقدمه: RS67333 آگونیست انتخابی گیرنده 4 سیستم سروتونرژیک(5-HT4) و ACPA (Arachidonylcyclopropylamide) آگونیست انتخابی گیرنده 1 سیستم کانابینرژیک(CB1) می باشد. هدف از این پژوهش بررسی اثر تزریق دو طرفه RS67333 در هیپوکامپ پشتی(CA1)، بر فرایند تشکیل حافظه ترس القاء شده توسط ACPA در موش های کوچک آزمایشگاهی نر بالغ بوده است. مواد و روش ها: 120 سر موش کوچک آزمایشگاهی نر نژاد NMRI در محدوده وزنی...
[ 7 ] - prelimbic of medial prefrontal cortex GABA modulation through testosterone on spatial learning and memory
Prefrontal cortex (PFC) is involved in multiple functions including attentional , spatial orientation, short and long-term memory. Our previous study indicated that microinjection of testosterone in CA1 impaired spatial learning and memory. Some evidence suggests that impairment effect of testosterone is mediated by GABAergic system. In the present study, we investigated the interaction of test...
[ 8 ] - prelimbic of medial prefrontal cortex GABA modulation through testosterone on spatial learning and memory
Prefrontal cortex (PFC) is involved in multiple functions including attentional , spatial orientation, short and long-term memory. Our previous study indicated that microinjection of testosterone in CA1 impaired spatial learning and memory. Some evidence suggests that impairment effect of testosterone is mediated by GABAergic system. In the present study, we investigated the interaction of test...
[ 9 ] - Evaluation of Pain Tolerance Threshold Following Anti TNF-α after Induction REM Sleep Deprivation in a Male Wistar Rat Model (In press)
Background and Aim: Tumor Necrose Factor-alpha (TNF-α) changes by REM sleep deprivation. Some believe that TNF-α is a biomarker in the deprivation of REM sleep. The patients with insomnia could be better after using Anti TNF-α or Infliximab (IFX), on the other hand, IFX effects on Patient Tolerance Threshold (PTT). Trying to manage the hospital inpatients’ pain is one of the common aims special...
[ 10 ] - Investigating the Effect of Anodal tDCS on Sustained Attention in Patients with MS
Multiple sclerosis is a de-myelinating inflammatory condition of the central nervous system that is often thought of as an autoimmune disorder. These patients suffer from extensive cognitive impairments such as poor attention and concentration and memory and processing speed; Therefore, the aim of this study was to investigate the anodic effect of direct cortical electrical stimulation (tDCS) o...
Co-Authors