Seyed Javad Hajmiresmail
Department of cardiology, Iran University of Medical Sciences, Tehran, Iran.
[ 1 ] - Plasma oxysterol level in patients with coronary artery stenosis and its changes in response to the treatment with atorvastatin
Background: Considering the increasing incidence of coronary artery stenosis and its related complications, the importance of its etiology and inconsistent reports we aimed to determine the relationship between oxysterol, serum levels and severity of coronary atherosclerosis and effect of statins on oxysterol. Methods: A total of 85 patients referred to Taleghani Hospital, Tehran, Iran during...
[ 2 ] - ATP-dependent potassium channels are implicated in simvastatin pretreatment-induced inhibition of apoptotic cell death after renal ischemia/reperfusion injury
Background: Simvastatin is a widely used medication in cardiac care. Here we evaluate the role of ATP sensitive potassium (KATP) channels in simvastatin induced renal protection after renal ischemia/reperfusion (I/R) injury. Methods: A total of 81 male Wistar rats, were treated with simvastatin (10 and 20mg/kg/day gavage, one week). Some groups received glibenclami...