حاجی فتعلی, عباس

علوم پزشکی شهید بهشتی

[ 1 ] - بررسی تاثیر ریتم شبانه روزی بر ترشح آدرنالین و نور آدرنالین و ارتباط ان با میزان موبیلیزاسیون سلول های بنیادی CD34

Hematopoietic stem cells (HSCs), which have the ability to differentiate into various types of blood cell lines, are usually separate from the bone marrow. But these cells are also present in a small amount in the peripheral blood, and their amounts increase in blood following injection of G-CSF. However, the mechanism involved in moving HSCs under the influence of G-CSF is unknown. The aim of ...

[ 2 ] - Signaling pathways involved in chronic myeloid leukemia pathogenesis: the importance of targeting Musashi2-Numb signaling to eradicate leukemia stem cells

Objective(s): Chronic myeloid leukemia (CML) is a myeloid clonal proliferation disease defining by the presence of the Philadelphia chromosome that shows the movement of BCR-ABL1. In this study, the critical role of the Musashi2-Numb axis in determining cell fate and relationship of the axis to important signaling pathways such as Hedgehog and Notch that are essential ...

[ 3 ] - Evaluation of ATG7 and Light Chain 3 (LC3) Autophagy Genes Expression in Newly Diagnosed AML Patients

Evaluation of ATG7 and LC3 Autophagy Genes Expression in Newly Diagnosed AML patients Background and aim: Autophagy, known as cell death type II, is a housekeeping pathway that currently has been worked on in matters of tumorigenesis and leukemogenesis. Therefore, in this study expression levels of ATG7 and LC3 as two key genes are targeted in AML patients. Material and method: This...

[ 4 ] - Evaluation of ATG7 and Light Chain 3 (LC3) Autophagy Genes Expression in Newly Diagnosed AML Patients

Evaluation of ATG7 and LC3 Autophagy Genes Expression in Newly Diagnosed AML patients Background and aim: Autophagy, known as cell death type II, is a housekeeping pathway that currently has been worked on in matters of tumorigenesis and leukemogenesis. Therefore, in this study expression levels of ATG7 and LC3 as two key genes are targeted in AML patients. Material and method: This...