دهقانی اشکذری, محمود
مرکز تحقیقات زیست فناوری پزشکی، واحد اشکذر، دانشگاه آزاد اسلامی، اشکذر، یزد، ایران
[ 1 ] - بررسی ارتباط پلی مورفیسم Val/Met ژن BDNF با بروز بیماری در بیماران آلزایمری و مقایسه آن با افراد سالمند سالم در ایران
Background: Alzheimer's disease is the most common cause of dementia in the elderly and the genetic and environmental factors interfere with its creation. The BDNF gene is responsible for producing a brain-derived neuronal factor. In this disease, the valine66methionine polymorphism and nucleotide changes of 196 (G>A) BDNF are genetic risk factors .This polymorphism has not been investigated in p…
[ 2 ] - Designing and optimization of liposomal nano-carriers containing Nepeta persica extract and study of its cytotoxicity on the breast cancer cell line (MCF-7)
Introdution: Studies have shown that plant compounds have significant anticancer effects that if the challenges of using them are resolved, can be the successor to the synthetic compounds commonly used in cancer therapy. Therefore, in this study, the liposomal nano- carriers containing Nepeta persica extract have been investigated in order to improve the physicochemical characteristics and evalua…
[ 3 ] - Association between HOXA10 (rs267601473) polymorphism and recurrent spontaneous abortion
Introduction: Recurrent spontaneous abortion is defined as the occurrence of more than two clinical miscarriages in one woman. Several factors, including endocrine irregularities, genetics and environmental factors, are involved in this kind of infertility.The aim of this study was to survey the association of HOXA10 (rs267601473) polymorphism with the risk of recurrent spontaneous abortion in ou…
[ 4 ] - Designing and Characterizing Nano-carriers Containing Nepeta Persica Extract and Their Effect on Bone Cancer
Aims Niosomes have been considered as carriers for targeted delivery of drugs in modern drug delivery systems. The Iranian Nepta (Nepta genus) has unique biological properties; thus, this plant was used in this study to prepare the optimized formulation of niosomes containing extract, and to evaluate its cytotoxicity. Methods & Materials Initially, the extract of Iranian Nepta (N. persica) was pr…