R Fardid
Assistant Professor, Radiology Department, School of Paramedical Sciences, Shiraz university of Medical Sciences, Shiraz, Iran
[ 1 ] - Evaluating Gamma-H2AX Expression as a Biomarker of DNA Damage after X-ray in Angiography Patients
Objective: Coronary heart disease (CHD) is one of the most common diseases. Coronary angiography (CAG) is an important apparatus used to diagnose and treat this disease. Since angiography is performed through exposure to ionizing radiation, it can cause harmful effects induced by double-stranded breaks in DNA which is potentially life-threatening damage. The aim of the present study is to investi…
[ 2 ] - Effects of Hesperidin as a Radio-protector on Apoptosis in Rat Peripheral Blood Lymphocytes after Gamma Radiation
Introduction: Hesperidin (HES), as the most abundant flavonoid existing in the citrus, is widely used by human daily. The radio-protective effects of Hesperidin have been confirmed in various measurement systems. This study aimed to evaluate the effects of Hesperidin on the changes in the apoptosis level and expression of apoptotic genes target (bax, bcl-2 and ration of bax/bcl-2) in the peripher…
[ 3 ] - Evaluating Radioprotective Effect of Hesperidin on Acute Radiation Damage in the Lung Tissue of Rats
Background: Oxidative stress plays an important role in the pathogenesis and progression of γ-irradiation-induced cellular damage, Lung is a radiosensitive organ and its damage is a dose-limiting factor in radiotherapy. The administration of dietary antioxidants has been suggested to protect against the succeeding tissue damage. The present study aimed to evaluate the radioprotective efficacy of…
[ 4 ] - The Mechanisms of Radiation-Induced Bystander Effect
The radiation-induced bystander effect is the phenomenon which non-irradiated cells exhibit effects along with their different levels as a result of signals received from nearby irradiated cells. Responses of non-irradiated cells may include changes in process of translation, gene expression, cell proliferation, apoptosis and cells death. These changes are confirmed by results of some In-Vivo stu…
[ 5 ] - Histopathologic Evaluation of Radio-Protective Effect of Hesperidin on the Liver of Sprague Dawely Rats
Objective: In this article aims to investigate the radio-protective effect of hesperidin on the liver of Sprague Dawely rats.Material and Methods: 40 male Sprague Dawely rats were selected randomly and divided into 8 groups. Group 1 did not receive radiation and hesperidin (sham control). Group 2 received only 100 mg/kg body weight (b.w) of hesperidin for 7 consecutive days (HES group); group 3 e…
[ 6 ] - Muc-1 Family Tumor Markers and Their Role in the Diagnosis of Breast Cancer, Review Article
Background & Objective: Tumor markers are elements produced by tumors or other cells in the body in response to cancer or some benign condition. Although most of these markers are made by normal cells as well as cancer cells, they are produced at much higher levels in cancerous conditions. This study aimed to provide a method for using tumor markers to diagnose cancer and detect the presence of m…
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