سید عباس طباطبایی یزدی

رییس گروه بخش پاتولو‍ژی دانشگاه علوم پزشکی مشهد، مشهد، ایران.

[ 1 ] - بررسی ایمونوهیستولوژیک بیانHER2 و P53 در مننژیوم و ارتباط آنها با درجه هیستولوژیک

مقدمه مننژیوم شایع‎ترین تومور داخل جمجمه‎ای اولیه با فراوانی قریب 30% می‎باشد. سیستم تقسیم بندی WHO 2007 مننژیوم را به سه درجه تقسیم کرده است. عود زودهنگام شایع‎ترین سناریوی شکست درمان جراحی مننژیوم است.HER2 یک پروتئین غشایی با فعالیت تیروزین کینازی میباشد که در سرطان‎های مختلف از جمله آدنوکارسینوم پستان افزایش بیان آن مشاهده شده است و هدف درمان دارویی با Herceptin می‎باشد.P53 یک ژن سرکوب کنند...

[ 2 ] - Prevalence of Atherosclerotic Plaques in Autopsy Cases with Noncardiac Death

  Background and Objective: Ischemic heart disease (IHD) following atherosclerosis is the most common cause of cardiac deaths world wide. We aimed to investigate the pathologic features of atherosclerosis in non cardiac death cases to have an estimate of atherosclerosis prevalence in Mashad (North east of Iran). Patients and Methods : This descriptive (cross sectional) study was done, during ...

[ 3 ] - Effect of Sprayed Cultured Autologous Keratinocyte Suspension Used Alone and in Combination with Fibrin Glue to Closure of 3rd Degree Burn Wounds in

Objective- Our point is to determine if the treatment of the 3rd degree burn wounds makes any difference if sprayed cultured autologous keratinocyte used alone or in combination with Fibrin glue. Design- Animal experimental study. Animals- 30 male Wistar rats. Procedures- Thirty male Wistar rats were selected and their keratinocytes were isolated and cultured from small skin biops...

[ 4 ] - Effect of crocin, an active saffron constituent, on ethanol toxicity in the rat: histopathological and biochemical studies

Objective(s): The drinking of ethanol causes the wide range of clinical illness and morphological changes including hepatotoxicity and nephrotoxicity. In the current study, the protective properties of crocin versus oxidative stress, apoptosis and inflammation induced by ethanol were assessed. Materials and Methods: The male Wistar rats ...

[ 5 ] - Investigating specific expression of ADAM29, FTHL17, and HORMAD1 cancer/testis genes in glioblastoma tumors

Introduction: Glioblastoma primary brain tumor.Immunotherapy is a promising therapeutic adjuvant in fighting against this cancer.  Cancer/testis antigens (CTAs) are a group of tumor-associated antigens that are typically restricted to adult testis, but they are aberrantly expressed in several types of cancers, especially in advanced cancers with stem-like characteristics. These tumor-associate...