اثر مکمل های رژیمی بر پارامتر های آزمایشگاهی و بیوشیمیایی ورزشکاران

Introduction: Since the use of supplements has increased among athletes, seriously warnings about the effects of their usage must also be taken. Therefore, this study examines the interaction of some commonly used supplements and biochemical laboratory parameters based on structural equation modeling. Materials and Methods: 40 male of bodybuilder subjects and forty male as controls between 20-40 years were chosen randomly. Athletes were consumed supplements including hormonal and non-hormonal for at least 6 months. Then biochemical and hematological parameters were measured and compared between two groups. Based on structural equation model, the role of dietary supplement on demographic, hematological and biochemical parameters were evaluated. Results: The mean (±SD) age of the athletes was 25±4.2 years. Only 15% of athletes were consuming between 1 to 2 cigarettes per day. White blood cells, platelets, blood urea nitrogen (BUN), creatinine (P = 0.001), aspartate aminotransferase (AST) (P = 0.005), and alanine aminotransferase (ALT) (P = 0.001) and partially the distribution of red blood cell (RDW) (0.063) were higher in athletes than to the controls. Based on structural equation model, the relationship between diatry supplements and laboratory parameters were significant (P = 0.01) and several parameters, including creatinine (P = 0.05), AST (P = 0.001), ALT (P = 0.001), and the RDW (P = 0.046) had more significant impact than others.   Conclusion: This study highlights the deleterious effects of supplements without a prescription and strongly suggests that there is some concern about the possible undesirable side effect induced by supplement.