بررسی فراوانی درگیری قلب در 61 کودک مبتلا به بیماری کاوازاکی

Kawasaki syndrome is an inflammatory multiorgan disease of unknown etiology. The most dramatic organ involved is the heart. There were a few studies about cardiac involvement in Iranian pediatric cases of Kawasaki disease. The aims of this study were determination of cardiac involvement prevalence in Iranian children with Kawasaki disease and its comparison with other studies. 61 pediatric cases of Kawasaki disease referred to pediatric clinic of Shahid Rajayee Heart Hospital during 7.5 years were studied for cardiac involvement retrospectively and prospectively. 41 cases(69%) did not have any sign of cardiac involvement. Coronary artery aneurism was detected in 8 cases(13%). Pericardial effusion was seen in 11%. There were EKG changes and cardiomegaly each in 8% of patients. Mild mitral regurgitation was seen in 10%. Combined treatment with aspirin and intravenous immunoglobulin led to less aneurisms than treatment with aspirin alone. Our study showed that Kawasaki patients need traditional treatment(aspirin and intravenous immunoglobulin) for decreasing the probability of cardiac involvement. Pericardial effusion was less prevalent in our study which may be due to less frequent echocardiographic examinations and evanescent nature of those effusions. We recommend that our colleagues refer Kawasaki patients to pediatric cardiologist for better assessment of their cardiovascular status.