Application of dimeric ortho-palladated complex of 2-methoxyphenethylamine in the Heck coupling reaction

نویسندگان

  • Abdol Hajipour Pharmaceutical Research Laboratory, Department of Chemistry, Isfahan University of Technology, Isfahan 84156, Iran. Department of Pharmacology, University of Wisconsin, Medical School, 1300 University Avenue, Madison, 53706-1532, WI, USA
  • Fatemeh Abrishami Pharmaceutical Research Laboratory, Department of Chemistry, Isfahan University of Technology, Isfahan 84156, Iran.
چکیده مقاله:

The application of the [Pd{C6H3(CH2CH2NH2)-4-OMe-5-κ2-C,N}(μ-Br)]2 complex of 2-methoxyphenethylamine in the Heck coupling reaction was considered under both conventional and microwave irradiation conditions, and their results were compared. This complex is an efficient, stable and non-sensitive to air and moisture catalyst for the vinylation of substituted aryl halides with different electronic properties. The cross-coupled products were produced in good to excellent yields using a catalytic amount of this complex in N-methyl-2-pyrrolidone (NMP) at 130 °C. In comparison to conventional heating conditions, the reactions under microwave irradiation gave higher yields in shorter reaction times.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

application of dimeric ortho-palladated complex of 2-methoxyphenethylamine in the heck coupling reaction

the application of the [pd{c6h3(ch2ch2nh2)-4-ome-5-κ2-c,n}(μ-br)]2 complex of 2-methoxyphenethylamine in the heck coupling reaction was considered under both conventional and microwave irradiation conditions, and their results were compared. this complex is an efficient, stable and non-sensitive to air and moisture catalyst for the vinylation of substituted aryl halides with different electroni...

متن کامل

Application of dimeric and monomeric ortho-palladated complexes as an efficient catalysts for Heck cross-coupling reaction

The catalytic acvtivity of dimeric and monomeric ortho-palladated complexes [Pd{C6H2(CH2NH2-(OMe)2,3,4}(µ-Cl)]2)2) and [Pd{C6H2(CH2NH2-(OMe)2,3,4}Cl(PPh3)](3), was investigated in Heck cross-coupling reaction. These complexes are more active and efficient catalysts for Heck cross-coupling reaction. The palladium complexes 2 and 3 is employed in the Heck cross-coupling reaction between styrene a...

متن کامل

application of dimeric and monomeric ortho-palladated complexes as an efficient catalysts for heck cross-coupling reaction

the catalytic acvtivity of dimeric and monomeric ortho-palladated complexes [pd{c6h2(ch2nh2-(ome)2,3,4}(µ-cl)]2)2) and [pd{c6h2(ch2nh2-(ome)2,3,4}cl(pph3)](3), was investigated in heck cross-coupling reaction. these complexes are more active and efficient catalysts for heck cross-coupling reaction. the palladium complexes 2 and 3 is employed in the heck cross-coupling reaction between styrene a...

متن کامل

Suzuki-Miyaura cross-coupling reaction catalyzed using highly efficient CN-dimeric ortho-palladated complex under microwave irradiation and conventional heating

Suzuki cross-coupling reaction of different aryl halides with arylboronic acids was successfully carried out in methanol using ortho-palladated complex of 2-methoxyphenethylamine. All substrates afforded the corresponding products in good to high yields in the presence of low amounts of this complex as efficient and active catalyst. Application of microwave irradiation improved the yields of th...

متن کامل

Suzuki-Miyaura cross-coupling reaction catalyzed using highly efficient CN-dimeric ortho-palladated complex under microwave irradiation and conventional heating

Suzuki cross-coupling reaction of different aryl halides with arylboronic acids was successfully carried out in methanol using ortho-palladated complex of 2-methoxyphenethylamine. All substrates afforded the corresponding products in good to high yields in the presence of low amounts of this complex as efficient and active catalyst. Application of microwave irradiation improved the yields of th...

متن کامل

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ذخیره در منابع من قبلا به منابع من ذحیره شده

{@ msg_add @}


عنوان ژورنال

دوره 2  شماره 3

صفحات  95- 100

تاریخ انتشار 2012-09-01

با دنبال کردن یک ژورنال هنگامی که شماره جدید این ژورنال منتشر می شود به شما از طریق ایمیل اطلاع داده می شود.

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023