P58: Neurological Outcomes after Traumatic Brain Injury Affected by Concomitant Administration of Progesterone and Erythropoietin

نویسندگان

  • Eshaghabadi, Arezou Shefa Neuroscience Research Center, Khatam Alanbia Hospital, Tehran, Iran.
  • Ghadiri, Tahere Shefa Neuroscience Research Center, Khatam Alanbia Hospital, Tehran, Iran.
  • Nourzad, Zahra Shefa Neuroscience Research Center, Khatam Alanbia Hospital, Tehran, Iran.
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p58: neurological outcomes after traumatic brain injury affected by concomitant administration of progesterone and erythropoietin

traumatic brain injury (tbi) is one of the most common neurological diseases with no definite treatment. erythropoietin (epo) and progesterone (prog) have been shown to have neuroprotective effects in different types of experimental brain injury models. this study was designed to determine the effect of epo, prog and combination of epo/prog on neurological outcome after traumatic brain injury. ...

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P80: The Effects of Progesterone Receptors\' Antagonist RU-486 on BrainEdema, Intracranial Pressure and Neurological Outcomes after Traumatic Brain Injury

In previous studies, the neuroprotective effect of progestrone in diffuse traumatic brain injury has been shown. This study used mifepristone (RU-486), a potent progesterone receptor antagonist, to evaluatethe hypothesis that the neuroprotective effect of progesterone in traumatic brain injury is mediated by the progesterone receptors. The ovariectomized rats were divided into 6 groups. Brain i...

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The Effects of Estrogen Receptors' Antagonist on Brain Edema, Intracranial Pressure and Neurological Outcomes after Traumatic Brain Injury in Rat

Background: In previous studies, the neuroprotective effect of 17&beta-estradiol in diffuse traumatic brain injury has been shown. This study used ICI 182,780, a non-selective estrogen receptor antagonist, to test the hypothesis that the neuroprotective effect of 17&beta-estradiol in traumatic brain injury is mediated by the estrogen receptors. Methods: The ovariectomized rats were divided into...

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p86: effect of concomitant use of erythropoietin and progesterone in traumatic brain injury

traumatic brain injuries may cause some neurological deficits, such as altered level of consciousness or coma, sensory-motor dysfunction, and seizure attacks. the neuroprotective effect of progesterone and erythropoietin has been shown in different types of brain injuries and cerebral ischemia. this study aims to evaluate the probable additional neuroprotective effects of progesterone and eryth...

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عنوان ژورنال

دوره 2  شماره 4

صفحات  108- 108

تاریخ انتشار 2014-12

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