Screening of Methicillin and Vancomycin resistant Staphylococcus aureus in the nasal of hospital personnel of Khorram Abad ,Iran

Abstract Background and Objectives associated infections has been gained attention by most researchers. We designed this cross-sectional study to evaluate MRSA and VRSA frequency in the Shohadai Ashayer hospital of Khorram Abad, Iran. : Increased drug resistance, and its Material and Methods: moistened with normal saline from interior nares of 300 personnel and immediately cultured on a Mannitol Salt Agar.Suspected colonies were confirmed by biochemical methods. Methicillin and Vancomycin resistance of isolated strains was carried out by agar dilution according to recommendations of National Clinical Laboratory Institute. Samples were obtained by sterile swab Results: carriers of S.aureus. 16 (5.33%) and 4 (1.33%) of the carriers were Methicillin resistant S.aureus (MRSA) and Vancomycin resistant S.aureus (VRSA), respectively. One (0.33%) of the personnel was concurrently the carrier of both MRSA and VRSA.No correlation was found between carriage and factors such as sex, age, ward of hospital and length of occupation, and predisposing diseases. Kind of occupation and level of education were significantly related with carrier state.(P<0.05) Sixty-four (21.33%) of 300 studied personnel were nasal Conclusion consistent with other published reliable documents. Isolation of four VISA and one VRSA strains from studied personnel was the interesting findings of this study. Because of carrying of such resistant strains in hospital personnel and risks of transmission to patients, it needs further attention of health officials. : Percentage of S.aureus carriers in hospital personnel was Keywords: Keywords: (MRSA), Vancomycin resistant S.aureus (VRSA), Vancomycin intermediate S.aureus (VISA),Carrier, Khorram Abad, IRAN Staphylococcus aureus, Methicillin resistant S.aureusStaphylococcus aureus, Methicillin resistant S.aureus