The effect of combined solution of grape vinegar and rose water versus chlorhexidine on oral health-related quality of life in patients undergoing chemotherapy

Aims  Improving oral hygiene is a part of the nursing care in oncology centers and its maintenance can also play an important role in improving Oral Health Related Quality of Life (OHRQOL). This study was conducted to investigate the effect of natural grape vinegar and rose water solution on oral health-related quality of life in patients undergoing chemotherapy. Material and Methods  A randomized controlled trial was conducted on 60 patients undergoing chemotherapy. Patients were randomly assigned to one of two groups of intervention and control. The participants rinsed their mouths with grape vinegar and rose water solution for one minute three times a day for 14 days. Oral Health Impact Profile was used for data collection. Data were analyzed by SPSS  software, using descriptive statistics methods and inferential analysis tests include independent sample t-test. Finding The global mean score of oral health related quality of life in the chlorhexizine group were 31.8±4.8 and19.5±4.6 for one day before the intervention and 21 day after the intervention ,respectively . These values for patients in the grape vinegar and rose water group were 30.8 ±6.3 and 14.1±4.1, respectively. The independent sample t-test showed a significant difference between the two groups at 21 days after the intervention. Conclusion  Natural solution of grape vinegar and rose water was useful to improve OHRQOL in patients undergoing chemotherapy.