The Relationship between Frequency of Restless leg Syndrome and Type 2 diabetes

Objective: Diabetes Mellitus (DM) is one of the most common metabolicdisorders. &nbsp;It is assumed that restless leg syndrome (RLS) occur more in diabetics. Our study aims to investigate the relationship between DM and restless leg syndrome. Materials and Methods: Our study conducted as a Case- control study, containing 180 patients as the cases and 201 as the controls from June 2016 to March 2017, at Ziyaiyan hospital, Tehran. All participants aged above 18 years. Data was collected by filling the pre-prepared checklists, complementary laboratory tests and precise physical examination by a single medical doctor. Results: The study was carried out with 318 participants, 163 (42.8%) were male and 218 (57.2%) female, total mean age was 52.2 16.3 years, BMI in case group and control group was 28.6 4.9and28.6 4.1 respectively. There was no statistically significant difference between the genders, mean age and BMI in two groups (P-value= 0.14, 0.14 and 0.56). RLS had a higher prevalence in Diabetic mans (P=value 0.04) with no significant difference in non-diabetics (P-value=0.21). RLS was more common in Diabetics (p-value=0.001) and they have 1.79 &ndash;fold higher risk of RLS (P-value<0.052). Conclusion: According to our findings, diabetic patients have increased risk of RLS. Diabetes can be considered as one of its risk factors; besides, the signs resemble diabetic neuropathy; therefore, we recommend accurate screening tests and immediate diagnosis and treatment perform in all diabetic patients. &nbsp;