Theoretical evaluation of medicinal properties for some of N-aryl-3-hydroxypyridine-4-ones derivative compounds

نویسندگان

  • Lotfollah Saghaie Department of Medicinal Chemistry, Faculty of Pharmacy, Isfahan University of Medical Sciences, Hezar Jerib, 81746-73461 Isfahan, I. R. of Iran.
  • Mohsen Oftadeh Chemistry Department, Payame Noor University, 19395-4697 Tehran, Iran
  • Shahla Pirialam Chemistry Department, Payame Noor University, 19395-4697 Tehran, Iran
چکیده مقاله:

Today, the bidentate ligands 3-hydroxypyridin-4-ones (HPOs) as orally active iron chelating agents have been demonstrated to possess potential for treatment of some human diseases such as iron-overload in thalassaemic patients and malaria. In this research, a series of HPOs with different substitutes and position were theoretically invest

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theoretical evaluation of medicinal properties for some of n-aryl-3-hydroxypyridine-4-ones derivative compounds

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عنوان ژورنال

دوره 2  شماره Issue 2, pp. 82-163

صفحات  82- 92

تاریخ انتشار 2014-04-01

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