Seyed Javad Sayedi

Department of Pediatrics, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

[ 1 ] - Immunomodulation of TLR2 and TLR4 by G2013 (alfa-L-Guluronic acid) in CVID Patients

Background: Common variable immunodeficiency (CVID) is a primary immune disorder associated with hypogammaglobulinemia, recurrent infections and autoimmune diseases. CVID patients are frequently in contact with infectious pathogens leading to the activation of innate immunity through Toll-like receptors (TLR) affecting adaptive immunity. The aim of the present study was to test the immunomedula...

[ 2 ] - The Prevalence of Portal Vein Thrombosis in Children under 3 Years Old with History of Neonatal Umbilical Vein Catheterization in the Neonatal Intensive Care Unit

Background Portal vein thrombosis (PVT) is one of the most common causes of extrahepatic portal hypertension in children, which may follow neonatal umbilical vein catheterization. The incidence rates of catheter-related PVT, in infants and children vary in different studies. This study aimed to determine PVT incidence in the children under 3 years old with a history of neonatal umbilical vein c...

[ 3 ] - A Case of Pulmonary Foreign Body Reviewed as Mass

Foreign Body Aspiration (FBA) is a common and sometimes life-threatening problem in children and in higher age groups. FBA highest incidence rate is during the second year in children and the sixth decade of life in adults, and often foreign bodies due to their shape and size pass through larynx and trachea and place in bronchi. The most common aspirated body by children are nuts. Symptoms of a...

[ 4 ] - Alpha- 1 Antitrypsin Deficiency in Children: Pulmonary Involvement

Introduction: α1-antitrypsin deficiency (α1-ATD) is one of the most common genetic disorders in white race, a usual cause of liver disease in children, and hepatopulmonary involvement in children and adult. The aim of this case description is presenting a child with early lung disease without liver parenchymal disorder. Case presentation: We describe a 13 year old boy because of exertional dysp...

[ 5 ] - Child Labor Facts in the Worldwide: A Review Article

The economic exploitation of children is an insult to humanity. All over the world children continue to work, putting at stake their education, their health, their normal development to adulthood, and even their lives. Millions of them work under hazardous conditions which present dangers to their health, safety and welfare. They toil in mines and quarries, are exposed to agrochemicals in agric...