Akram Astani

Department of Microbiology, School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

[ 1 ] - Evaluating cytotoxic effects of recombinant fragaceatoxin C pore forming toxin against AML cell lines

Objective(s): Current therapeutic strategies for cancer are associated with side effects and lack of specificity in treatments. Biological therapies including monoclonal antibodies and immune effectors have been the subject of multiple research projects. Pore-forming proteins may become the other biological strategy to overcome the problems associated with current treatments. But detailed mecha...

[ 2 ] - بررسی شیوع هپاتیت G در اهداکنندگان خون مراجعه‌کننده به سازمان انتقال خون یزد در سال 91

Introduction: Hepatitis G virus is an RNA virus related to Flaviviridae family that its genome was identified in the patients with non A-E hepatitis at the end of the last century. The present study aimed to investigate the survey of the prevalence of hepatitis G in blood donors and its relation to age and gender Methods: In this descriptive cross-sectional study, sampling was performed on 263...

[ 3 ] - Carvacrol Ameliorates Pathological Cardiac Hypertrophy in Both In-vivo and In-vitro Models

Hypertension-induced left ventricular hypertrophy is the most important risk factor for heart failure. This study aimed at investigating the effects of monoterpenoid phenol, carvacrol, on myocardial hypertrophy using both in-vivo and in-vitro models. Male Wistar rats were divided into the control (Ctl), un-treated hypertrophy (H), and carvacrol-treated hypertrophy gro...

[ 4 ] - Carvacrol Ameliorates Pathological Cardiac Hypertrophy in Both In-vivo and In-vitro Models

Hypertension-induced left ventricular hypertrophy is the most important risk factor for heart failure. This study aimed at investigating the effects of monoterpenoid phenol, carvacrol, on myocardial hypertrophy using both in-vivo and in-vitro models. Male Wistar rats were divided into the control (Ctl), un-treated hypertrophy (H), and carvacrol-treated hypertrophy gro...

[ 5 ] - The Effect of Temperature and Acidity on ‎Antimicrobial Activities of Pristine ‎MWCNTs and MWCNTs-Arg

   Carbon nanotubes (CNTs) have very promising applications for inhibition of microbial growth. The aim of this study is investigation and comparison of the effect of temperature and acidity on antimicrobial activities of pristine Multiwalled Carbon nanotubes (MWCNTs) and Multiwalled Carbon nanotubes-Arginine (MWCNTs-Arg). Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Conc...

[ 6 ] - Frequency of fimH, papC, and aer in E. coli Strains Isolated from Patients with Urinary Tract Infection, and their Antibiotic Resistance Pattern

Introduction: E. coli is the predominant causes of urinary tract infection. Several virulence factors for bacterial infections in the urinary tract are required. In this study, we have considered several virulence factors in strains isolated from the patients with UTI in Yazd. Methods: In this cross-sectional study in 1394-1395, 146 strains isolated were collected from the patients with urinar...