Zhiqing Cai

Department of Orthopedics, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China, 510120

[ 1 ] - Wear particles enhance autophagy through up-regulation of CD147 to promote osteoclastogenesis

Objective(s): The study aimed to uncover the underlying mechanism linking wear particles to osteoclast differentiation, and we explored the effect of titanium particles of different sizes on CD147 expression and autophagy in macrophages. Materials and Methods: Effects of titanium particles on CD147 and RANKL mRNA were detected by QPCR; protein level of CD147 and Beclin-1 were detected by Wester...

نویسندگان همکار

Baohua Su 1  

Deng Li 1  

Jie Xu 1  

Ruofan Ma 1  

Yingbin Zhang 1