Masoumeh Fakhr Taha
Department of Stem Cells and Regenerative Medicine, Institute for Medical Biotechnology, National Institute of Genetic Engineering and Biotechnology (NIGEB), Tehran, Iran
[ 1 ] - Extract of mouse embryonic stem cells induces the expression of pluripotency genes in human adipose tissue-derived stem cells
Objective(s): In some previous studies, the extract of embryonic carcinoma cells (ECCs) and embryonic stem cells (ESCs) have been used to reprogram somatic cells to more dedifferentiated state. The aim of this study was to investigate the effect of mouse ESCs extract on the expression of some pluripotency markers in human adipose tissue-derived stem cells (ADSCs). Materials and Methods: Human A...
[ 2 ] - بهبود تمایز قلبی سلولهای بنیادی بافت چربی انسانی با استفاده از ترکیب bFGF و BMP4
Background and Aim: Adipose-derived stem cells (ADSCs) represent a promising source of cells for cardiac tissue engineering and repair of the injured heart. However, better understanding of the factors affecting the cardiac differentiation of ADSCs is required before clinical application of these cells. Current study was designed to investigate the role of bFGF and BMP4 in cardiac differentiati...
[ 3 ] - Reprogramming by cytosolic extract of human embryonic stem cells improves dopaminergic differentiation potential of human adipose tissue-derived stem cells
The extract of pluripotent stem cells induces dedifferentiation of somatic cells with restricted plasticity. In this study, we used the extract of human embryonic stem cells (hESC) to dedifferentiate adipose tissue-derived stem cells (ADSCs) and examined the impact of this reprogramming event on dopaminergic differentiation of the cells. For this purpose, cytoplasmic extract of ESCs was prepare...
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