Iraj Yazdani
Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran|Experimental Medicine Research Center, Tehran University of Medical Sciences, Tehran, Iran
[ 1 ] - Rapamycin protects testes against germ cell apoptosis and oxidative stress induced by testicular ischemia-reperfusion
Objective(s):Rapamycin is an immunosuppressant compound with a broad spectrum of pharmaco-logical activities. In recent years, it has been used successfully to decrease ischemia-reperfusion injury in several organ systems. The purpose of the present study was to examine the effect of rapamycin on testicular ischemia-reperfusion injury. Materials and Methods: Seventy-two adult male Wistar rats w...
[ 2 ] - Minocycline attenuates cirrhotic cardiomyopathy and portal hypertension in a rat model: Possible involvement of nitric oxide pathway
Objective(s): An increase in nitric oxide (NO) production has been reported in cirrhotic cardiomyopathy and, portal hypertension. Since minocycline has been shown to inhibit NO overproduction, we aimed to examine its role in a rat model of CCl4-induced cirrhotic cardiovascular complications. Materials and Methods: Portal pressure and inotropic responsiveness of isolated papillary muscles to is...
نویسندگان همکار