Jin Li
Department of Laboratory, Zhongnan Hospital of Wuhan University, Wuhan, China
[ 1 ] - Antioxidant properties of repaglinide and its protections against cyclosporine A-induced renal tubular injury
Objective(s): Repaglinide (RG) is an antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus. It has a good safety and efficacy profile in diabetic patients with complications in renal impairment and is an appropriate treatment choice, even for individuals with more severe degrees of renal malfunctions. The aim of the present study was to examine the protective...
[ 2 ] - Therapeutic effect of valsartan against doxorubicin-induced renal toxicity in rats
Objective(s): Doxorubicin (DXR)-induces glomerular atrophy and fibrosis in rat kidneys. The objective of the current study was to investigate the protective effects of valsartan on DXR-induced glomerular toxicity and its mechanisms of actions in rats. Materials and Methods: Male Sprague-Dawley (SD) rats were divided into four groups, and each group contains ten rats. First group was control and...
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