Fengchun Deng

Department of Anatomy, Qiqihar Medical University, Qiqihar, Heilongjiang, China, 161006

[ 1 ] - The role of noggin in regulation of high glucose-induced apoptosis and insulin secretion in INS-1 rat beta cells

Objective(s):The purpose of this study was to investigate the effects of Noggin on high glucose-induced apoptosis and insulin secretion in pancreatic beta cells. Materials and Methods: Different concentrations of glucose were used to examine their effects on INS-1 rat beta cells in vitro. When specific siRNA targeting Noggin and recombinant Noggin were added, apoptosis and insulin secretion wer...

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