Mohsen Minaiyan
Department of Pharmacology and Toxicology and Isfahan Pharmaceutical Research Center, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, Iran
[ 1 ] - Antinociceptive effects of maprotiline in a rat model of peripheral neuropathic pain: possible involvement of opioid system
Objective(s): Neuropathic pain remains a clinical problem and is poorly relieved by conventional analgesics. This study was designed to determine whether maprotiline administration was effective in alleviating symptoms of neuropathic pain and whether the antinociceptive effect of maprotiline mediated through the opioid system. Materials and Methods: Neuropathic pain was induced by chronic cons...
[ 2 ] - The anti-inflammatory effects of venlafaxine in the rat model of carrageenan-induced paw edema
Objective(s):Recently anti-inflammatory effects of antidepressants have been demonstrated. Venlafaxine belongs to newer antidepressants with serotonin norepinephrine reuptake inhibition property. The pain alleviating properties of venlafaxine in different pain models such as neurogenic pain, diabetic neuropathy, and fibromyalgia have been demonstrated. Anti-inflammatory effects of venlafaxine a...
[ 3 ] - Effect of Hydroalcoholic and Buthanolic Extract of Cucumis sativus Seeds on Blood Glucose Level of Normal and Streptozotocin-Induced Diabetic Rats
Objective(s) Seed of Cucumis sativus Linn. is one of the herbal remedies has been traditionally used for diabetes mellitus treatment. We studied the effect of hydroalcoholic and buthanolic extract obtained from C. sativus seeds in a model of streptozotocin (STZ)-induced diabetic (type I) rats. Materials and Methods Normal and diabetic male Wistar rats (STZ, 60 mg/kg, intraperitoneal) were tr...
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