Fatemeh Amiri

Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran, Iran

[ 1 ] - The Lcn2-engineered HEK-293 cells show senescence under stressful condition

Objective(s): Lipocalin2 (Lcn2) gene is highly expressed in response to various types of cellular stresses. The precise role of Lcn2 has not been fully understood yet. However, it plays a key role in controlling vital cellular processes such as proliferation, apoptosis and metabolism. Recently it was shown that Lcn2 decreases senescence and increases proliferation of mesenchymal stem cells (MSC...

[ 2 ] - Cell Survival Effects of Autophagy Regulation on Umbilical Cord-Derived Mesenchymal Stem Cells Following Exposure to Oxidative Stress

Background: Due to oxidative stress, hypoxia, and serum deprivation, a large percentage of mesenchymal stem cells (MSCs) die in the early stages of transplantation. The present study aimed to address whether induction or inhibition of autophagy would affect the viability of MSCs after exposure to oxidative stress.Methods: MSCs were isolated from umbilical cord tissue using the Ficoll grad...

[ 3 ] - Survey on Laboratory Test Quality Control Establishment in Public and Private Medical Laboratories in Hamedan Province

Introduction: The purpose of laboratory test quality control establishment is to ensure the daily stability of the test system. Considering the defined principles guarantees laboratory performance improvement and patients’ confidence in the results of their tests. This study was conducted to survey laboratory test quality control establishment in public and private medical laboratories in Hamed...

[ 4 ] - Survey on non-Conformities Reported in Public and Private Medical Laboratories of Hamadan Province

Introduction: Clinical laboratory is a workplace where a variety of diagnostic tests are performed and it plays an important role in the diagnosis, treatment and prevention of diseases. Non-conformity does not meet the predetermined requirements. Laboratory nonconformities influence laboratory test results. Addressing of non-conformities is essential for laboratory improvement. The aim of this ...

[ 5 ] - Survey on Audit Process of Medical Laboratories in Hamadan Province

Introduction: Audit is an organized and documented process in which qualified and trained auditors evaluate the laboratories using tools such as checklists. This study was designed and conducted to survey the audit process in medical laboratories of Hamadan province. Methods and Materials: This study was cross-sectional and retrospective research. Laboratories of Hamadan province were studied ...

[ 6 ] - Evaluation of Correlation between D-dimer Levels with Disease Severity in Patients with Covid-19 Referred to Hamedan Besat Hospital in 2021-2022

Introduction: The Covid-19 virus affects the hemostasis system in infected people by causing thrombosis and it increases the level of D_dimer. This study was designed and conducted for the evaluation of correlation between D-dimer levels with disease severity in patients with Covid-19 referred to Hamedan Besat hospital. Methods and Materials: 366 patients with Covid-19 referred to Besat Hospit...