Eskandar Moghimipour
Nanotechnology Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran 2 School of Pharmacy, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
[ 1 ] - Preparation and Characterization of Cyanocobalamin (Vit B12) Microemulsion Properties and Structure for Topical and Transdermal Application
Objective(s): The objective of this study was to design a topical microemulsion of Vit B12 and to study the correlation between internal structure and physicochemical properties of the microemulsions. Microemulsions are thermodynamically stable mixtures of water, oil, surfactants and usually cosurfactants with several advantages for topical and transdermal drug delivery. The formul...
[ 2 ] - تهیه و ارزیابی ویژگی لیپوزوم های اشریشیاکلی به عنوان یک سیستم دارو رسانی نوین به سلول های سرطانی کولون
مقدمه: لیپوزومها ذرات کروی شکل متشکل از دو لایه فسفولیپیدی و دارای ویژگی محصورسازی داروهای آب دوست و آب گریز هستند. امکان ساخت لیپوزومها با استفاده از فسفولیپیدهای طبیعی، لیپیدهای سنتزی و یا لیپیدهای باکتریایی وجود دارد. این پژوهش با هدف تولید لیپوزومها با استفاده از لیپیدهای غشایی باکتری اشریشیا کلی و ردیابی آن در رده سلولی HT29 انجام گرفت. مواد و روش ها: پژوهش حاضر به شکل تجربی بر ر...
[ 3 ] - Antifungal and antibacterial activities of polyherbal toothpaste against oral pathogens, in vitro
Background and Purpose: Herbal toothpastes are more secure and efficacious and less poisonous due to containing natural chemicals as compared with the synthetic toothpastes. The present study aimed to formulate a polyherbal toothpaste using accessible medicinal plants in Iran and evaluate its efficiency in the protection of oral hygiene and prevention of dental caries. Materials and Methods:...
[ 4 ] - The Effect of Various Penetration Enhancers on the Octyl Methoxycinnamate Permeability: Mechanisms of Action Study
Octyl methoxycinnamate is one of the ingredients in sunscreen products. The main aim of this study was to investigate the effect of different enhancers of in vitro skin permeability of Octyl methoxycinnamate. Octyl methoxycinnamate permeability parameters were evaluated through the whole skin of the rat with and without chemical enhancers including eucalyptus oil, urea, menthol and olive ...
[ 5 ] - Evaluation of the influence of chamomile vaginal gel on dyspareunia and sexual satisfaction in postmenopausal women: A randomized, double-blind, controlled clinical trial
Objective: The purpose of this study was to determine the effect of chamomile vaginal gel on dyspareunia and sexual satisfaction in postmenopausal women. The phytoestrogenic properties of Matricaria chamomilla were the reason for selection of this plant. Materials and Methods: This double-blind clinical trial research was conducted on 96 eligible postmeno...
[ 6 ] - Tadalafil Transdermal Drug Delivery Using Microemulsion Formulation in Laboratory Model
Background and purpose: Tadalafil has gained wide clinical acceptance in treatment of erectile dysfunction due to its long treatment window and lower potential for visual impairment. Transdermal drug delivery prevents systemic elimination, drug-drug and food-drug interactions, and reduces side effects by reducing the dose of the drug. The aim of this study was to evaluate the effect of microemu...
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