Amir Hassan Zarnani
Department of Immunology, Tarbiat Modarres University | Department of Immunology, Monoclonal Antibody Research Center, Avesina Research Institute, Tehran, Iran and
[ 1 ] - Indoleamine 2,3-Dioxygenase and Immunological Tolerance during Pregnancy
Indoleamine 2,3-dioxygenase (IDO), an enzyme involved in the catabolism of tryptophan, is expressed by a variety of cells and tissues such as macrophages, dendritic cells, cells of the endocrine system and by the placenta. IFN- γ is the main inducer of this enzyme. IDO acts as an important defense mechanism of innate immunity against pathogens. It also has tumor suppressive activity and prolong...
نویسندگان همکار