Mohammad Jahanbakhshi

Neuroscience Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran

[ 1 ] - The role of BK channels in antiseizure action of the CB1 receptor agonist ACEA in maximal electroshock and pentylenetetrazole models of seizure in mice

The anticonvulsant effect of cannabinoid compound has been shown in various models of seizure. On the other hand, there are controversial findings about the role of large conductance calcium-activated potassium (BK) channels in the pathogenesis of epilepsy. In this study, the effect of arachidonyl-2′-chloroethylamide (ACEA), a CB1 receptor agonist, and a BK channel antagonist, paxilline, either...

[ 2 ] - The role of BK channels in antiseizure action of the CB1 receptor agonist ACEA in maximal electroshock and pentylenetetrazole models of seizure in mice

The anticonvulsant effect of cannabinoid compound has been shown in various models of seizure. On the other hand, there are controversial findings about the role of large conductance calcium-activated potassium (BK) channels in the pathogenesis of epilepsy. In this study, the effect of arachidonyl-2′-chloroethylamide (ACEA), a CB1 receptor agonist, and a BK channel antagonist, paxilline, either...

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