Kamla Pathak

[ 1 ] - Norfloxacin loaded pH triggered nanoparticulate in situ gel for extraocular bacterial infections: Optimization, ocular irritancy and corneal toxicity

In order to achieve prolong corneal contact time of norfloxacin(NFX) for treatment of extra ocular diseases, a pH triggered nanoparticulate in situ gelling system was designed to explore dual advantage of nanoparticles and in situ gelling system, for its ocular delivery. NFX loaded nanocarriers were developed by ionotropic gelation technique using chitosan as a matrix forming polymer, cross-lin...

[ 2 ] - Preparation, Characterization and Pharmacodynamic Evaluation of Fused Dispersions of Simvastatin using PEO-PPO Block Copolymer

The solubility enhancement of poorly soluble compounds is an important task in pharmaceutical technology as it leads to better bioavailability and a more efficient application. Fused dispersions (FDs) of simvastatin (SIM) using PEO-PPO block copolymer were prepared which paved the way for the formation of an amorphous product with enhanced dissolution and bioavailability. The accumulative s...

[ 3 ] - Norfloxacin loaded pH triggered nanoparticulate in situ gel for extraocular bacterial infections: Optimization, ocular irritancy and corneal toxicity

In order to achieve prolong corneal contact time of norfloxacin(NFX) for treatment of extra ocular diseases, a pH triggered nanoparticulate in situ gelling system was designed to explore dual advantage of nanoparticles and in situ gelling system, for its ocular delivery. NFX loaded nanocarriers were developed by ionotropic gelation technique using chitosan as a matrix forming polymer, cross-lin...

[ 4 ] - Preparation, Characterization and Pharmacodynamic Evaluation of Fused Dispersions of Simvastatin using PEO-PPO Block Copolymer

The solubility enhancement of poorly soluble compounds is an important task in pharmaceutical technology as it leads to better bioavailability and a more efficient application. Fused dispersions (FDs) of simvastatin (SIM) using PEO-PPO block copolymer were prepared which paved the way for the formation of an amorphous product with enhanced dissolution and bioavailability. The accumulative s...