Maryam Noubarani

Department of Pharmacology and Toxicology, School of Pharmacy, Zanjan University of Medical Sciences, Zanjan, Iran.

[ 1 ] - Hypolipidemic, hepatoprotective and renoprotective effects of Cydonia oblonga Mill. Fruit in streptozotocin-induced diabetic rats

Diabetes mellitus is associated with complications in several different systems of the body, and the incidence of diabetes is rapidly increasing worldwide. The objective of the present study was to evaluate the effect of aqueous extract of Cydonia oblonga Mill. Fruit on lipid profile and some biochemical parameters in streptozotocin-induced diabetic rats. The extract showed anti hyper lipidemic...

[ 2 ] - Determination of Mebudipine in Human Plasma by Liquid Chromatography–tandem Mass Spectrometry

In previous studies, mebudipine, a dihydropyridine calcium channel blocker, showed a considerable potential to be used in cardiovascular diseases. The aim of the current study was to develop a valid method using reversed-phase high performance liquid chromatography coupled with electrospray ionization mass spectrometry to assay mebudipine in the human plasma. Separation was achieved on a Zorbax...

[ 3 ] - Effect of Adiantum Capillus veneris Linn on an Animal Model of Testosterone-Induced Hair Loss

Androgenetic alopecia is the most common form of hair loss in men. The present study was designed to evaluate the hair growth-promoting activity of a preparation of the Adiantum capillus veneris Linn. (A. capillus veneris Linn.) on albino mice using a testosterone-induced alopecia model. Five groups of albino mice were studied: (A) Testosterone solution only (n=6); (B) Testosterone ‏+ Finasteri...

[ 4 ] - Hypolipidemic, hepatoprotective and renoprotective effects of Cydonia oblonga Mill. Fruit in streptozotocin-induced diabetic rats

Diabetes mellitus is associated with complications in several different systems of the body, and the incidence of diabetes is rapidly increasing worldwide. The objective of the present study was to evaluate the effect of aqueous extract of Cydonia oblonga Mill. Fruit on lipid profile and some biochemical parameters in streptozotocin-induced diabetic rats. The extract showed anti hyper lipidemic...

[ 5 ] - Determination of Mebudipine in Human Plasma by Liquid Chromatography–tandem Mass Spectrometry

In previous studies, mebudipine, a dihydropyridine calcium channel blocker, showed a considerable potential to be used in cardiovascular diseases. The aim of the current study was to develop a valid method using reversed-phase high performance liquid chromatography coupled with electrospray ionization mass spectrometry to assay mebudipine in the human plasma. Separation was achieved on a Zorbax...

[ 6 ] - Effect of Adiantum Capillus veneris Linn on an Animal Model of Testosterone-Induced Hair Loss

Androgenetic alopecia is the most common form of hair loss in men. The present study was designed to evaluate the hair growth-promoting activity of a preparation of the Adiantum capillus veneris Linn. (A. capillus veneris Linn.) on albino mice using a testosterone-induced alopecia model. Five groups of albino mice were studied: (A) Testosterone solution only (n=6); (B) Testosterone ‏+ Finasteri...

[ 7 ] - The Role of Olea Europaea L. Fruit on A2780, A172 and HFFF2 Proliferation

Olea europaea L. commonly known as olive has been traditionally used for the prevention and treatment of many diseases since ancient times. Olive has been reported to possess a broad spectrum of pharmacological properties. In the present study we investigated the activity of aqueous extract of Olea europaea L. fruit at various concentrations on A2780, A172 and HFFF2 cell lines proliferation by ...

[ 8 ] - Prescription Pattern of Corticosteroids in Zanjan, Iran

The aim of the present study was to provide a clear picture of the prescribing pattern of corticosteroids in Zanjan, Iran. A retrospective and cross-sectional study was conducted to describe the pattern of corticosteroids prescription at Beheshti pharmacy (Zanjan, Iran) over a period of six months between March 21 and September 22 of 2013. Descriptive analyses were stratified by gender, age, typ...

[ 9 ] - Phoenix dactylifera L. Fruit Induces Cell Proliferation of A2780, A172 and HFFF2 Cell Lines

Dates fruit has been used as staple food in the Middle East for thousands of years and various types of dates are found worldwide. Dates and their constituents show various roles in diseases prevention and treatment through anti-oxidant, anti-inflammatory, anti-bacterial activity. In the present study we investigated the activity of aqueous and n-hexane extracts of Phoenix dactylifera L. fruit ...

[ 10 ] - A search for protective activity of aqueous extract of Punica granatum var. pleniflora against CCl4-induced hepatotoxicity in rats

Background: Punica granatum var. pleniflora (Golnar in Persian) is a subspecies of pomegranate that only has the blooms with no fruit generation. The plant has been used for the treatment of liver diseases in Iranian folk medicine. Objective: In the present study, the hepatoprotective effects of aqueous extract of Punica granatum var. pleniflora (APG) were evaluated in carbon tetrachloride (CCl...