Ibolya Fülöp
University of Medicine and Pharmacy Targu Mures, Faculty of Pharmacy, Department of Toxicology and Biofarmacy
[ 1 ] - Cyclodextrine Screening for the Chiral Separation of Carvedilol by Capillary Electrophoresis
Carvedilol is administered as a racemic mixture of the R(+)- and S(-)-enantiomers, although it was demonstrated that the two enantiomers exhibit different pharmacological effects and stereoselective pharmacokinetics. The aim of this study was the evaluation of several native and derivatized cyclodextrines as chiral selectors for the separation of carvedilol enantiomers. Stereoselective interact...
[ 2 ] - Cyclodextrine Screening for the Chiral Separation of Carvedilol by Capillary Electrophoresis
Carvedilol is administered as a racemic mixture of the R(+)- and S(-)-enantiomers, although it was demonstrated that the two enantiomers exhibit different pharmacological effects and stereoselective pharmacokinetics. The aim of this study was the evaluation of several native and derivatized cyclodextrines as chiral selectors for the separation of carvedilol enantiomers. Stereoselective interact...
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