Ahmad Ghorbani

Pharmacological Research Center of Medicinal Plants, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, IRAN

[ 1 ] - Effect of Zirconium Dioxide Nanoparticles on Glutathione Peroxidase Enzyme in PC12 and N2a Cell Lines

Objective: Today, special attention is paid to the use of zirconium dioxide nanoparticle (nano-ZrO2), a neutral bioceramic metal, particularly for drug and gene delivery in medicine. However, there are some reports implying that use of nano-ZrO2 is associated with cytotoxic effects like inhibiting the cell proliferation, DNA damage and apoptosis. In the present study, we examined whether nano-Z...

[ 2 ] - Potentiating Effects of Lactuca sativa on Pentobarbital-Induced Sleep

Traditionally, Lactuca sativa (lettuce) has been recommended for its hypnotic property.The present study was planned to investigate sleep-prolonging effect of this plant. The hydroalcoholicextract (HAE) of lettuce and its water fraction (WF), ethyl acetate fraction (EAF),and n-butanol fraction (NBF) were administrated (IP) to mice 30 min before the pentobarbitalinjection. Moreover, both in-vivo...

[ 3 ] - Effect of Zirconium Dioxide Nanoparticles on Glutathione Peroxidase Enzyme in PC12 and N2a Cell Lines

Objective: Today, special attention is paid to the use of zirconium dioxide nanoparticle (nano-ZrO2), a neutral bioceramic metal, particularly for drug and gene delivery in medicine. However, there are some reports implying that use of nano-ZrO2 is associated with cytotoxic effects like inhibiting the cell proliferation, DNA damage and apoptosis. In the present study, we examined whether nano-Z...

[ 4 ] - Potentiating Effects of Lactuca sativa on Pentobarbital-Induced Sleep

Traditionally, Lactuca sativa (lettuce) has been recommended for its hypnotic property.The present study was planned to investigate sleep-prolonging effect of this plant. The hydroalcoholicextract (HAE) of lettuce and its water fraction (WF), ethyl acetate fraction (EAF),and n-butanol fraction (NBF) were administrated (IP) to mice 30 min before the pentobarbitalinjection. Moreover, both in-vivo...

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