Varsha Sarode
P.D.V.V.P.F’s College of Pharmacy, Vilad Ghat, Ahmednagar, 414111, India.
[ 1 ] - Synthesis, Spectral Characterization and Analgesic Activity of 2-Methylthio-1, 4-Dihydropyrimidines
A series of 2-methylthio-1,4-dihydropyrimidine derivatives (II) were synthesized in good yields by alkylation of 1,2,3,4-tetrahydropyrimidines (I) with methyl iodide in the presence of pyridine. Their structures were confirmed by elemental analysis, IR and 1H NMR spectra. The compounds were tested for analgesic activity by acetic acid induced writhing method. Compounds IIh, IIe, IIk and IIl sho...
[ 2 ] - Synthesis, Spectral Characterization and Analgesic Activity of 2-Methylthio-1, 4-Dihydropyrimidines
A series of 2-methylthio-1,4-dihydropyrimidine derivatives (II) were synthesized in good yields by alkylation of 1,2,3,4-tetrahydropyrimidines (I) with methyl iodide in the presence of pyridine. Their structures were confirmed by elemental analysis, IR and 1H NMR spectra. The compounds were tested for analgesic activity by acetic acid induced writhing method. Compounds IIh, IIe, IIk and IIl sho...
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