Chhaganbhai Patel

Department of Pharmaceutics, C. U. Shah College Institute of Pharmacy and Research Wadhwan, Gujarat, India.

[ 1 ] - Floating Matrix Tablets of Domperidone Formulation and Optimization Using Simplex Lattice Design

The purpose of this research was to prepare a floating matrix tablet containing domperidone as a model drug. Polyethylene oxide (PEO) and hydroxypropyl methylcellulose (HPMC) were evaluated for matrix-forming properties. A simplex lattice design was applied to systemically optimize the drug release profile. The amounts of PEO WSR 303, HPMC K15M and sodium bicarbonate were selected as independen...

[ 2 ] - Floating Matrix Tablets of Domperidone Formulation and Optimization Using Simplex Lattice Design

The purpose of this research was to prepare a floating matrix tablet containing domperidone as a model drug. Polyethylene oxide (PEO) and hydroxypropyl methylcellulose (HPMC) were evaluated for matrix-forming properties. A simplex lattice design was applied to systemically optimize the drug release profile. The amounts of PEO WSR 303, HPMC K15M and sodium bicarbonate were selected as independen...

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