Mohsen Khalili

Neurophysiology Research Center, Shahed University, Tehran, Iran

[ 1 ] - Effect of combination therapy with diazepam and glibenclamide on serum lipids and glucose in type 2 diabetic rats

Background and Objective: Several studies have found that diazepam decreases serum glucose. Meanwhile, glibenclamide is commonly used in diabetes treatment. The objective of this study was to survey the treatment impact of diazepam and glibenclamide on blood glucose and serum lipids in mice with type II diabetes. Materials and Methods: In this study, 32 male rats were divided into four groups,...

[ 2 ] - Dose-dependent effect of Hypericum perforatum extract on motor imbalance following intrastriatal injection of 6-hydroxydopamine in the rat

Background and Objective: Parkinson's disease (PD) is a neurodegenerative disease with selective damage of mesencephalic dopaminergic neurons. Due to the protective, anti-inflammatory, and antioxidant effect of Hypericum perforatum (HP), this study was undertaken to assess dose-dependent effect of HP hydroalcoholic extract on motor imbalance following intrastriatal injection of 6-hydroxydopamin...

[ 3 ] - Phytic Acid Mitigates Motor Asymmetry in Male Rat with Unilateral 6-Hydroxydopamine Striatal Lesion

Background and Objective: Parkinson's disease (PD) is a movement disorder with debilitating symptoms. Available treatments for PD mainly include its symptomatic relief with no prevention of its progression. Due to the iron-chelating and antioxidant effect of phytic acid (PA), this study was conducted to assess its protective effect in 6-hydroxydopamine-induced model of PD in rat. Materials and ...