Ali Niazi

[ 1 ] - Spectrophotometric Determination of Mefenamic Acid in Biological Samples Using Magnetic Iron Oxide Nanoparticles as a Sorbent for Solid Phase Extraction

This work investigates the potential of magnetic Fe3O4 nanoparticles as an adsorbent for separation and preconcentration of trace amounts of mefenamic acid in aquatic and biological samples, prior to spectrophotometric determination. The magnetic iron oxide nanoparticles (MIONs) were synthesized by mixing of ferrous and ferric chlorides. The possible parameters affecting the enrichment were opt...

[ 2 ] - Wavelength region selection and spectrophotometric simultaneous determination of naphthol isomers based on net analyte signal

Naphthol isomers were simultaneously and spectrophotometrically determined in wastewater, using a model based on net analyte signal (NAS). The calibration method used is a variation of the original hybrid linear analysis method as proposed by Goicoechea and Olivieri (HLA/GO). Owing to spectral interferences, the simultaneous determination of mixtures of naphthol isomers, using a spectrophotomet...

[ 3 ] - Determination of trace amounts of lead by adsorptive cathodic stripping voltammetry in the presence of xylenol orange

Lead forms the complexes with xylenol orange in the basic solution. An adsorptivedifferential pulse stripping method for the determination of lead is proposed. The procedureinvolves an adsorptive accumulation of lead on a hanging mercury drop electrode (HMDE) inthe presence of xylenol orange, followed by reduction of adsorbed lead by voltammetric scanusing differential pulse modulation. The opt...

[ 4 ] - سنتز نانو-ماکرو ساختار منیزیم اکسید به روش آسان بدون استفاده از ماده فعال در سطح و بررسی کاربرد آن در رهایش داروی نیفدیپین

در این پژوهش، نانو-ماکرو منیزیم اکسید به‌آسانی و با نسبت‌های متفاوتی از اسیدآمینه آرژنین و اوره (بدون استفاده از ماده فعال در سطح) با ساختارهای متفاوت مکعبی و کروی با روش آب‌گرمایی در دمای 130 تا 180 درجه سانتی‌گراد در مدت 24 ساعت سنتز شد و در دمای 400 و 600 درجه سانتی‌گراد کلسینه شد تا نانوذراتی بین 42 تا 80 نانومتر به‌دست آید. شش فراورده به‌دست آمده با روش‌های پراش پرتو ایکس (XRD)، میکروسکوپ ...

[ 5 ] - Partial Least Square and Parallel Factor Analysis Methods Applied for Spectrophotometric Determination of Cefixime in Pharmaceutical Formulations and Biological Fluid

In this study, the direct determination of cefixime as an anti-bacterial agent, in pharmaceutical formulations, urine and human blood plasma was conducted based on spectrophotometric measurements using parallel factor analysis (PARAFAC) and partial least squares (PLS). The calibration set was composed of fourteen solutions in the range of 0.50- 9.00 µg mL-1. PLS models were calculated at each p...

[ 6 ] - Pixel selection by successive projections algorithm method in multivariate image analysis for a QSAR study of antimicrobial activity for cephalosporins and design new cephalosporins

Thirty-one Cephalosporin compounds were modeled using the multivariate image analysis and applied to the quantitative structure activity relationship (MIA-QSAR) approach. The acid dissociation constants (pKa) of cephalosporins play a fundamental role in the mechanism of activity of cephalosporins. The antimicrobial activity of cephalosporins was related to their first pKa by different models. B...

[ 7 ] - Partial Least Square and Parallel Factor Analysis Methods Applied for Spectrophotometric Determination of Cefixime in Pharmaceutical Formulations and Biological Fluid

In this study, the direct determination of cefixime as an anti-bacterial agent, in pharmaceutical formulations, urine and human blood plasma was conducted based on spectrophotometric measurements using parallel factor analysis (PARAFAC) and partial least squares (PLS). The calibration set was composed of fourteen solutions in the range of 0.50- 9.00 µg mL-1. PLS models were calculated at each p...

[ 8 ] - Pixel selection by successive projections algorithm method in multivariate image analysis for a QSAR study of antimicrobial activity for cephalosporins and design new cephalosporins

Thirty-one Cephalosporin compounds were modeled using the multivariate image analysis and applied to the quantitative structure activity relationship (MIA-QSAR) approach. The acid dissociation constants (pKa) of cephalosporins play a fundamental role in the mechanism of activity of cephalosporins. The antimicrobial activity of cephalosporins was related to their first pKa by different models. B...

[ 9 ] - Application of Genetic Algorithms for Pixel Selection in MIA-QSAR Studies on Anti-HIV HEPT Analogues for New Design Derivatives

Quantitative structure-activity relationship (QSAR) analysis has been carried out with a series of 107 anti-HIV HEPT compounds with antiviral activity, which was performed by chemometrics methods. Bi-dimensional images were used to calculate some pixels and multivariate image analysis was applied to QSAR modelling of the anti-HIV potential of HEPT analogues by means of multivariate calibration,...

[ 10 ] - Combine flake like magnesium hydroxide and cubic like aluminum hydroxide nanostructures in order to improve fire retardant of PVC and PMMA

In this study, Flake-like magnesium hydroxide (Mg(OH)2) and cubic-like aluminum hydroxide (Al(OH)3) nanostructures were synthesized via a simple co-precipitation method at relatively low temperature. Chemical properties and surface morphology of the magnesium hydroxide and aluminum hydroxide were characterized by X-ray diffraction analysis (XRD), scanning electron microscopy image (SEM), transm...

[ 11 ] - Application of Genetic Algorithms for Pixel Selection in MIA-QSAR Studies on Anti-HIV HEPT Analogues for New Design Derivatives

Quantitative structure-activity relationship (QSAR) analysis has been carried out with a series of 107 anti-HIV HEPT compounds with antiviral activity, which was performed by chemometrics methods. Bi-dimensional images were used to calculate some pixels and multivariate image analysis was applied to QSAR modelling of the anti-HIV potential of HEPT analogues by means of multivariate calibration,...