Majid Farvardin-Jahromi

[ 1 ] - The relationship between NQO1 C609T and CAT C-262T genetic polymorphisms and the risk of age-related cataracts

Cataract is multi-factorial eye disease identified by the disturbance of the transparent ocular lens. There is significant evidence suggesting oxidative damage as a major cause of initiation and progression of numerous diseases including cataracts. NAD(P)H:quinone oxidoreductase 1 (NQO1; OMIM: 125860) and catalase (CAT, OMIM: 115500) are antioxidant enzymes that prevent cells from oxidative str...