Nioosha Nekooie-Marnany

Department of Biology, College of Sciences and Institute of Biotechnology, Shiraz University, Shiraz 71454, Iran

[ 1 ] - Effect of Cyclosporine A on the expression of GSTO2 metabolizing enzyme in Jurkat cell line

Cyclosporine A (CsA), a cyclic polypeptide metabolite extracted from the fungus, is used clinically to combat organ graft rejection in transplant subjects. Previous studies have shown that CsA exposure enhances the production of reactive oxygen species (ROS) and lipid peroxidation, which are directly involved in CsA toxicity. To protect cells and organs against ROS, the human body has evolved a...

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