Legha Ansari

School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran

[ 1 ] - The effect of mesoporous silica nanoparticles loaded with epirubicin on drug-resistant cancer cells

Objective (s): In chemotherapy for cancer treatment, the cell resistance to multiple anticancer drugs is the major clinical problem. In the present study, mesoporous silica nanoparticles (MSNs) were used as a carrier for epirubicin (EPI) in order to improve the cytotoxic efficacy of this drug against the P-glycoprotein (P-gp) overexpressing cell line. Materials and Methods: MSNs with phosphonat...

[ 2 ] - Silica -magnetic inorganic hybrid nanomaterials as versatile sensing platform

Several hybrid sensing materials, which are organized by interaction of organic molecules onto inorganic supports, have been developed as a novel and hopeful class of hybrid sensing probes. The hybrid silica-magnetic based sensors provide perfect properties for production of various devices in sensing technology. The hybridization of silica and magnetic NPs as biocompatible, biodegradable and s...