محمدخانی, اشرف

بیمارستان دکترعلی شریعتی تهران، تهران، ایران

[ 1 ] - بررسی تاثیرتکثیرHBV با سطح سرمی APRIL و بیان مارکر IgD بر سطحB Cell های بافت کبد در بیماران مبتلا به هپاتیت مزمن B

Introduction: Host immune responses are considered as an an important factor concerning the progression of HBV infection. B cells population following Hepatitis B infection has received scant attention. A Poroliferation-Inducing Ligand (APRIL) can be introduced as a stimulator of B cell activities. Therefore, this study intended to investigate the proportion of IgD positive B lymphocytes in liv...

[ 2 ] - The Increased Level of Serum p53 in Hepatitis B-Associated Liver Cirrhosis

Background: The ability of tumour suppressor protein p53 (P53) to regulate cell cycle processes can be modulated by hepatitis B virus (HBV). While preliminary evidences indicates the involvement of protein-x of HBV (HBx) in altering p53 DNA binding, no further data have been accumulated for the significance of serum p53 in chronic hepatitis B virus infected patients. Methods: 72 non-cirrhotic a...