مرتضی سمنانی, کتایون

[ 1 ] - بررسی پایداری فیزیکی حالت جامد و سازگاری پیروکسیکام با مواد جانبی قرص‌ها توسط روش‌های فیزیکوشیمیایی

Background and purpose: The pharmaceutical excipients can be incompatible with drug or other excipients. Thus, for each material, compatibility with formulation components and packaging materials should be examined. The dissolution of a drug has an important role in its bioavailability. Any change in the physico-chemical properties can result in changes in the drug release, and furthermore in i...

[ 2 ] - بررسی تأثیر اعمال حرارت بر کنترل سرعت آزادسازی تئوفیلین از ماتریس‌های حاوی پلیمرهای اودراجیت RS و M4K HPMC با استفاده از روش مایع به جامد

Background and purpose: The potential of liquisolid systems for increasing drug dissolution has been proved in many researches. Recent studies have shown that liquisolid technique is a new and promising method for controlling the dissolution rate of drugs. Based on thermal treating effect on polymer structure, in this study the effects of thermal treating on theophylline release from liquisolid...